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The Impact of FDG PET on the Management of Occult Primary Head and Neck Tumours by W.L. Wong; M. Saunders is a Agricultural and Biological Sciences article available to read on EtoBox.

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## Aims: The aim of this study was to investigate the impact of positron-emission tomography (PET) with 18F-labelled fluoro-2deoxy-D-glucose (FDG) in the management of occult primary head and neck tumours. Materials and methods: We reviewed 16 patients with squamous cell carcinoma (SCC) and one patient with undifferentiated carcinoma of cervical lymph nodes (N1-4; N2a-9; N2b-2; N3-2). All patients had full clinical assessment, including examination under anaesthesia (EUA), with biopsy of all suspicious areas and random biopsies of sites likely to harbour an occult primary site. Nine patients underwent magnetic resonance imaging (MRI) of the head and neck, three underwent computed tomography (CT) and five underwent both CT and MRI. None of these studies were able to locate a primary tumour. Patients received 350 MBq FDG intravenously. Emission transmission scans of the extra-cranial head, neck and thorax were obtained using an ECAT Exact 47 at least 60 min after injection. The images were interpreted by the same radiologist experienced in PET, independent of the final outcome. The influence of FDG PET on management was assessed on review of the patients' notes after treatment or whe

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Author

W.L. Wong; M. Saunders

Publisher

Elsevier Science; Springer; Elsevier ; Springer-Verlag; W. B. Saunders Co., Ltd.; Springer Verlag; Elsevier BV; Springer Science and Business Media LLC (ISSN 1433-2981)

Published

2003

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)