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Can I read Exosomes as a Nano-Carrier for Chemotherapeutics: A New Era of Oncology on EtoBox?
Exosomes as a Nano-Carrier for Chemotherapeutics: A New Era of Oncology by Rodrigo Pinheiro Araldi; Denis Adrián Delvalle; Vitor Rodrigues da Costa; Anderson Lucas Alievi; Michelli Ramires Teixeira; João Rafael Dias Pinto; Irina Kerkis is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Exosomes as a Nano-Carrier for Chemotherapeutics: A New Era of Oncology about?
Despite the considerable advancements in oncology, cancer remains one of the leading causes of death worldwide. Drug resistance mechanisms acquired by cancer cells and inefficient drug delivery limit the therapeutic efficacy of available chemotherapeutics drugs. However, studies have demonstrated that nano-drug carriers (NDCs) can overcome these limitations. In this sense, exosomes emerge as potential candidates for NDCs. This is because exosomes have better organotropism, homing capacity, cellular uptake, and cargo release ability than synthetic NDCs. In addition, exosomes can serve as NDCs for both hydrophilic and hydrophobic chemotherapeutic drugs. Thus, this review aimed to summarize the latest advances in cell-free therapy, describing how the exosomes can contribute to each step of the carcinogenesis process and discussing how these nanosized vesicles could be explored as nano-drug carriers for chemotherapeutics.
Who reads Exosomes as a Nano-Carrier for Chemotherapeutics: A New Era of Oncology?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Rodrigo Pinheiro Araldi; Denis Adrián Delvalle; Vitor Rodrigues da Costa; Anderson Lucas Alievi; Michelli Ramires Teixeira; João Rafael Dias Pinto; Irina Kerkis
- Publisher
- MDPI AG
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)