Can I read Myelin Loss and Neuronal Hyperexcitability on EtoBox?

Myelin Loss and Neuronal Hyperexcitability by Frontiers is a document available to read on EtoBox.

What is Myelin Loss and Neuronal Hyperexcitability about?

This study investigates the effects of myelin loss on the excitability of neocortical neurons using a cuprizone mouse model. The findings reveal that demyelination leads to increased neuronal excitability and altered ion channel distribution, particularly affecting the axon initial segment (AIS) and facilitating ectopic action potential generation. These results suggest that myelination plays a crucial role not only in conduction velocity but also in regulating neuronal hyperexcitability in cortical pyramid

Author

Frontiers

Language

EN