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The study establishes a collagen gel contraction assay using human bronchial smooth muscle cells to evaluate the inhibitory effect of formoterol on histamine-induced contraction. Results indicate that formoterol inhibits gel contraction in a concentration-dependent manner, and that fluticasone enhances this inhibitory effect. The findings suggest that this assay is a useful tool for assessing bronchodilating drugs and their interactions with corticosteroids.

Author

mribsilva1994

Language

EN