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Biochemical fingerprint and pharmacological applications of Barleria noctiflora L.f. leaves by Sangilimuthu Alagar Yadav; Sathishkumar Ramalingam; Anitha Jebamalairaj; Ravi Subban; Karpagavalli Mennakshi Sundaram is a Medicine article available to read on EtoBox.

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Background: Antioxidant and antihistamine agents from Barleria noctiflora L.f. as natural source due to the existing modern medicine give various adverse effects to overcome these problems with natural products. Methods: B. noctiflora leaves extract was fractionated with column chromatography; the homogenized fractions were monitored with thin layer chromatography (TLC) and characterized by using UV-visible, FT-IR, 1 H NMR, 13 C NMR and mass spectrometry spectral studies. The volatile phytoconstituents of B. noctiflora extract were analysed by gas chromatography-mass spectrometry. Phytoconstituents from B. noctiflora leaves extract were screened for their antioxidant and antihistamine potential in vitro (2,2diphenyl-1-picrylhydrazyl radical scavenging activity, 2,2′azinobis-3-ethylbenzothiozoline-6-sulfonic acid radical decolouration assay, nitric oxide radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide radical scavenging activity) and in silico (molecular docking), respectively. Results: Antioxidant and antihistamine barlerinoside has been isolated and characterized from the leaves of B. noctiflora L.f. Barlerinoside revealed their free-radic

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Author

Sangilimuthu Alagar Yadav; Sathishkumar Ramalingam; Anitha Jebamalairaj; Ravi Subban; Karpagavalli Mennakshi Sundaram

Publisher

Walter de Gruyter GmbH

Published

2016

Language

EN

Field

Medicine (Health Sciences)