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Development and validation of the Exercise-Induced Laryngeal Obstruction Dyspnea Index (EILODI) by James Tod Olin; Monica Shaffer; Emily Nauman; Catherine S. Durso; Elizabeth M. Fan; Herman Staudenmayer; Kent L. Christopher; Jackie Gartner-Schmidt is a Medicine article available to read on EtoBox.

What is Development and validation of the Exercise-Induced Laryngeal Obstruction Dyspnea Index (EILODI) about?

## Background: Exercise-induced laryngeal obstruction (eilo) causes exertional dyspnea and is important for its effect on quality of life, diagnostic confusion with exercise-induced asthma, and health care resource utilization. there is no validated patient-reported outcome measure specific to eilo. ## Objective: We sought to develop, validate, and define a minimal clinically important difference for a patient-reported outcome measure to be used with adolescents and young adults with eilo. ## Methods: A multidisciplinary group created a preliminary measure, modified by a 10-member participant focus group, with 20 items scored along a 5-point likert scale. a subsequent cohort of participants recruited from a clinic, aged 12 to 21 years, with confirmed eilo by continuous laryngoscopy during exercise testing (1) completed the measure at 3 points in time over 28 days and (2) provided anchoring data in the form of a daily exercise log and categorical self-assessments of clinical improvement. thirty additional participants without exertional dyspnea served as controls. ## Results: Two hundred nineteen subjects with mild to severe eilo participated in the exploratory factor analysis, whic

Who reads Development and validation of the Exercise-Induced Laryngeal Obstruction Dyspnea Index (EILODI)?

Author

James Tod Olin; Monica Shaffer; Emily Nauman; Catherine S. Durso; Elizabeth M. Fan; Herman Staudenmayer; Kent L. Christopher; Jackie Gartner-Schmidt

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)