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The document discusses best practices for immunohistochemical assessment of PTEN in vulvar cancer tissue samples. It describes the methods used to stain 150 vulvar carcinoma tissue samples for PTEN, PI3K, AKT, and mTOR. Sharp and specific PTEN expression was observed in the nuclei and cytoplasm. PTEN expression levels ranged from 3.5 to 226 and correlated with higher patient survival rates. The study emphasizes the importance of standardized techniques for reliable PTEN evaluation in clinical practice.

Author

MuhammadRidwansyah

Language

EN