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Genetic Background Effects on Mice Phenotype by feemiki is a document available to read on EtoBox.

This document discusses genetic background effects and genetic modifiers of phenotype in mice. It notes that differences in phenotype between mouse strains are due to allelic variation in their genetic background. When a major gene mutation is introduced, its phenotypic effects can vary depending on the genetic background, as other genes can modify penetrance or expressivity. Introducing mutations onto a mixed genetic background, as in an F1 hybrid, has advantages like hybrid vigor but could also obscure th

Author

feemiki

Language

EN