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1. Renal failure results in various biochemical disturbances such as metabolic acidosis, hypokalemia, hyperkalemia, edema, and hypertension as kidney function deteriorates. 2. Symptoms of uremia include those related to fluid, electrolyte and acid-base imbalances as well as effects on other body systems like the cardiovascular, gastrointestinal and neurological systems. 3. Renal replacement therapy through either hemodialysis or peritoneal dialysis is needed when the GFR falls below a certain level, to

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nidhi261987

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