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In Search of an Algorithm to Prevent Acute Kidney Injury⁎⁎Editorials published in JACC: Cardiovascular Interventions reflect the views of the authors and do not necessarily represent the views of JACC: Cardiovascular Interventions or the American College of Cardiology. by Harold L. Dauerman is a Medicine article available to read on EtoBox.

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In this issue of JACC: Cardiovascular Interventions, Brown et al. (1) present a meta-analysis of 10 trials involving combined therapy with sodium bicarbonate (NaHCO 3 ) plus N-acetylcysteine (NAC) and demonstrate a significant reduction in acute kidney injury (AKI) with this regimen as compared with other prophylactic strategies. Given that the risk of contrast-induced AKI in high-risk patient groups might exceed 20% (2,3) and that AKI is associated with considerable morbidity (4), a simple strategy for AKI prophylaxis could potentially lead to significant quality im-See page 1116 provement across cardiovascular catheterization laboratories. The authors conclude: "We recommend that a comprehensive prophylactic protocol needs to be incorporated into practice to prevent contrast-induced AKI, incorporating both NaHCO 3 and NAC." The precedent for a clearcut algorithm for care to improve outcomes has been established for interventional cardiology most notably with respect to primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Are we now ready to bring that same kind of clarity to an algorithm to prevent contrast-induced AKI? ## Where Consensus Res

Who reads In Search of an Algorithm to Prevent Acute Kidney Injury⁎⁎Editorials published in JACC: Cardiovascular Interventions reflect the views of the authors and do not necessarily represent the views of JACC: Cardiovascular Interventions or the American College of Cardiology.?

Author

Harold L. Dauerman

Publisher

American College of Cardiology; Elsevier ; Elsevier BV (ISSN 1936-8798)

Published

2009

Language

EN

Field

Medicine (Health Sciences)