Can I read Production of tumour-inhibitory lignans in callus cultures of Podophyllum hexandrum on EtoBox?
Production of tumour-inhibitory lignans in callus cultures of Podophyllum hexandrum by A. Gerard Heyenga; John A. Lucas; Paul M. Dewick is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Production of tumour-inhibitory lignans in callus cultures of Podophyllum hexandrum about?
Callus cultures have been established from root explants of aseptically-grown Podophyllum hexandrum seedlings. A fully defined medium based on Gamborg's B5 salts supplemented with 2/4-dichlorophenoxyacetic acid, gibberellic acid and 6-benzylaminopurine was effective for both initiation and sustained growth of callus tissue. Cultures produced anticancer lignans podophyllotoxin, 4'-demethylpodophyllotoxin and podophyllotoxin 4-O-glucoside at levels similar to those found in the expiant material as assayed by high performance liquid chromatography. The relative proportions of podophyllotoxin and 4'-demethyl-podophyllotoxin were markedly influenced by the presence of plant growth regulators. Particularly high levels of podophyllotoxin were associated with growth regulator induced tissue differentiation.
Who reads Production of tumour-inhibitory lignans in callus cultures of Podophyllum hexandrum?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- A. Gerard Heyenga; John A. Lucas; Paul M. Dewick
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0721-7714)
- Published
- 1990
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)