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This study investigates the correlation between blood-based extracellular matrix biomarkers and clinical outcomes in metastatic melanoma patients treated with PD-1 inhibitors. High levels of type III collagen and vimentin turnover were associated with worse progression-free survival (PFS) and overall survival (OS), while an increase in vimentin levels after treatment correlated with improved OS. These findings suggest that these biomarkers may help predict responses to immunotherapy in this patient populati

Author

Ciro Dantas Soares

Language

EN