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The Surface Contour of Articular Cartilage in an Intact, Loaded Joint by J. M. CLARK; A. G. NORMAN; M. J. KÄÄB; H. P. NÖTZLI is a Earth and Planetary Sciences article available to read on EtoBox.

What is The Surface Contour of Articular Cartilage in an Intact, Loaded Joint about?

The friction coefficients measured in diarthrodial joints are small. Theories of joint lubrication attribute this efficiency to entrapment or movement of synovial fluid, yet anatomical models of the surface are based on studies of isolated fragments of cartilage, not functional joints. To investigate the functional interrelationship of joint surfaces and synovial fluid, the ultrastructure of loaded joints was examined. Twenty‐four New Zealand white rabbit knee joints were loaded either statically or moved ex vivo using simulated muscle forces and then plunge‐frozen under load. After fixation in the frozen/loaded state by freeze‐substitution fixation, the medial joint compartments were embedded in epoxy resin while still articulated. Bone was trimmed away from the articular surfaces, permitting the cartilage to be sectioned for light and electron microscopy. These joint surfaces were then compared with controls which were not loaded, not moved or had been disarticulated prior to embedding. Articular surfaces of loaded joints were smooth at magnifications from ×35 to ×7500, whereas the tibial surfaces of nonloaded joints were irregular. Small pools of joint fluid were observed at the

Who reads The Surface Contour of Articular Cartilage in an Intact, Loaded Joint?

Author

J. M. CLARK; A. G. NORMAN; M. J. KÄÄB; H. P. NÖTZLI

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0021-8782)

Published

1999

Language

EN

Field

Earth and Planetary Sciences (Physical Sciences)