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Can I read Cobalt-Catalyzed, Directed C–H Functionalization/Annulation of Phenylglycinol Derivatives with Alkynes on EtoBox?
Cobalt-Catalyzed, Directed C–H Functionalization/Annulation of Phenylglycinol Derivatives with Alkynes by Jekaterina Bolsakova; Lukass Lukasevics; Liene Grigorjeva is a Chemistry article available to read on EtoBox.
What is Cobalt-Catalyzed, Directed C–H Functionalization/Annulation of Phenylglycinol Derivatives with Alkynes about?
A new method for cobalt-catalyzed C(sp)-H functionalization of phenylglycinol derivatives with terminal and internal alkynes directed by picolinamide auxiliary has been developed. This method offers an efficient and highly regioselective route for the synthesis of 1-hydroxymethyltetrahydroisoquinolines. The reaction employs commercially available Co(II) catalyst in the presence of Mn(III) cooxidant and oxygen as a terminal oxidant and proceeds with full preservation of original stereochemistry.
Who reads Cobalt-Catalyzed, Directed C–H Functionalization/Annulation of Phenylglycinol Derivatives with Alkynes?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Jekaterina Bolsakova; Lukass Lukasevics; Liene Grigorjeva
- Publisher
- American Chemical Society; American Chemical Society (ACS) (ISSN 0022-3263)
- Published
- 2020
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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