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Copper Homeostasis and Copper-induced Cell Death in the Pathogenesis of Cardiovascular Disease and Therapeutic Strategies by Xinyue Chen; Qi Cai; Ruikai Liang; Deju Zhang; Xiao Liu; Meiying Zhang; Yan Xiong; Minxuan Xu; Qi Liu; Pengyang Li; Peng Yu; Ao Shi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Copper Homeostasis and Copper-induced Cell Death in the Pathogenesis of Cardiovascular Disease and Therapeutic Strategies about?
## Abstract Copper is a vital mineral, and an optimal amount of copper is required to support normal physiologic processes in various systems, including the cardiovascular system. Over the past few decades, copper-induced cell death, named cuproptosis, has become increasingly recognized as an important process mediating the pathogenesis and progression of cardiovascular disease (CVD), including atherosclerosis, stroke, ischemia-reperfusion injury, and heart failure. Therefore, an in-depth understanding of the regulatory mechanisms of cuproptosis in CVD may be useful for improving CVD management. Here, we review the relationship between copper homeostasis and cuproptosis-related pathways in CVD, as well as therapeutic strategies addressing copper-induced cell death in CVD.
Who reads Copper Homeostasis and Copper-induced Cell Death in the Pathogenesis of Cardiovascular Disease and Therapeutic Strategies?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Xinyue Chen; Qi Cai; Ruikai Liang; Deju Zhang; Xiao Liu; Meiying Zhang; Yan Xiong; Minxuan Xu; Qi Liu; Pengyang Li; Peng Yu; Ao Shi
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)