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This study presents the design, synthesis, and biological evaluation of thiadiazole-isatin hybrid analogues as potential anti-diabetic and anti-bacterial agents. The synthesized compounds exhibited significant inhibitory activity against α-amylase and α-glucosidase enzymes, with some analogues showing promising results compared to the standard drug acarbose. Additionally, the structure-activity relationship analysis indicated that specific substituents on the phenyl ring influenced the inhibitory potential

Author

saad.a.aljadani

Language

EN