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Difference in Survival in Early Kidney after Liver Transplantation Compared with Simultaneous Liver-Kidney Transplantation: Evaluating the Potential of the “Safety Net” by Jay, Colleen L.; Washburn, W Kenneth; Rogers, Jeffrey; Harriman, David; Heimbach, Julie; Stratta, Robert J. is a Medicine article available to read on EtoBox.

What is Difference in Survival in Early Kidney after Liver Transplantation Compared with Simultaneous Liver-Kidney Transplantation: Evaluating the Potential of the “Safety Net” about?

## Background: Decisions on who requires simultaneous liver-kidney (slk) transplantation are controversial. united network for organ sharing implemented a "safety net" in 2017 providing prioritization on the kidney waitlist for patients with renal failure after liver transplantation. we aimed to compare survival after early kidney after liver transplantation (kalt) and slk. ## Study design: We compared slk, kalt, and liver transplantation alone (lta) in adult patients who underwent deceased donor (dd) liver transplantation in the us, from 2002 to 2018. early kalt was defined as 60 to 365 days between liver and subsequent kidney transplantation (reflecting safety net listing criteria). patients who died within 60 days were excluded to mitigate immortal time bias favoring kalt. ## Results: There were 6,774 slk, 120 kalt at 60 to 365 days, and 11,501 lta. early kalt had equivalent survival compared with slk, both for all kalt (hazard ratio [hr] 0.58, 95% ci 0.34-1.00, p = 0.05) and for dd kalt only (hr 0.72, 95% ci 0.37-1.38, p = 0.32). simultaneous liver-kidney transplantation was associated with improved survival compared with lta (hr 0.82. 95% ci 0.76-0.87, p < 0.01). early kalt wa

Who reads Difference in Survival in Early Kidney after Liver Transplantation Compared with Simultaneous Liver-Kidney Transplantation: Evaluating the Potential of the “Safety Net”?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Jay, Colleen L.; Washburn, W Kenneth; Rogers, Jeffrey; Harriman, David; Heimbach, Julie; Stratta, Robert J.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2020
Language
EN
Field
Medicine (Health Sciences)

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