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Prognostic significance of spontaneous shockable rhythm conversion in adult out-of-hospital cardiac arrest patients with initial non-shockable heart rhythms: A systematic review and meta-analysis by Shengyuan Luo; Yongshu Zhang; Wanwan Zhang; Ruiying Zheng; Jun Tao; Yan Xiong is a Medicine article available to read on EtoBox.

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Background: There remains controversy over the prognostic significance of spontaneous shockable rhythm conversion in out-of-hospital cardiac arrest (OHCA) patients with initial non-shockable heart rhythms (pulseless electrical activity [PEA] or asystole). The aim of this study was to examine the association of shockable rhythm conversion with multiple OHCA outcomes, and to explore effect modifiers. Methods: A dual-reviewer search was conducted in PubMed and EMBASE databases in March 2017. Data on study design, patient characteristics, outcomes, adjusting and stratifying variables were extracted. Estimates were combined using random-effects models. Results: Twelve studies involving 1,108,281 OHCA patients with initial non-shockable heart rhythms were identified using pre-specified eligibility criteria. Combined adjusted estimates showed that shockable rhythm conversion was associated with higher odds of pre-hospital return of spontaneous circulation (ROSC) (odds ratio [OR] =1.47, 95% confidence interval [CI] 1.40-1.55). Although shockable rhythm conversion was not associated with survival to hospital discharge (OR =1.36, 95% CI 0.77-2.38), it was associated with higher odds of one-m

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Author

Shengyuan Luo; Yongshu Zhang; Wanwan Zhang; Ruiying Zheng; Jun Tao; Yan Xiong

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Medicine (Health Sciences)