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Cephalosporins are a group of semisynthetic β-lactam antibiotics derived from cephalosporin-C, with a structure similar to penicillins and a broad spectrum of antibacterial activity. They are classified into four generations, with each subsequent generation exhibiting increased potency and a wider antibacterial spectrum, particularly against gram-negative bacteria. Clinical uses include treatment of bacterial infections, surgical prophylaxis, and management of meningitis, while resistance mechanisms are sim

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