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Can I read Five-year Kidney Outcomes of Bariatric Surgery Differ in Severely Obese Adolescents and Adults with and Without Type 2 Diabetes on EtoBox?
Five-year Kidney Outcomes of Bariatric Surgery Differ in Severely Obese Adolescents and Adults with and Without Type 2 Diabetes by Bjornstad, Petter; Nehus, Edward; Jenkins, Todd; Mitsnefes, Mark; Moxey-Mims, Marva; Dixon, John B.; Inge, Thomas H. is a Medicine article available to read on EtoBox.
What is Five-year Kidney Outcomes of Bariatric Surgery Differ in Severely Obese Adolescents and Adults with and Without Type 2 Diabetes about?
Bariatric surgery improves markers of kidney health in severe obesity, yet it is unclear if kidney disease outcomes differ according to age at surgery. Therefore, we examined health effects of Roux-en-Y gastric bypass between 161 adolescents and 396 adults participating in two related but distinct studies. Primary outcomes were elevated urine albumin-to-creatinine ratio (UACR) of 30 mg/g or more and hyperfiltration (an estimated glomerular filtration rate of 135 ml/min/1.73m or more). Analyses were stratified by the presence of pre-operative type 2 diabetes. Adolescents with pre-operative type 2 diabetes had a significantly increased prevalence of elevated UACR prior to surgery compared to adults (22.5 vs. 9.0%). Resolution of elevated UACR following surgery differed between adolescents and adults with type 2 diabetes, with adolescents experiencing a significantly earlier improvement following surgery. Adolescents without pre-operative type 2 diabetes demonstrated a significantly increased prevalence of UACR prior to surgery compared to adults (9.4 vs. 4.5%), with no improvement occurring in either group post-operatively. Adolescents with pre-operative type 2 diabetes had a signifi
Who reads Five-year Kidney Outcomes of Bariatric Surgery Differ in Severely Obese Adolescents and Adults with and Without Type 2 Diabetes?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Bjornstad, Petter; Nehus, Edward; Jenkins, Todd; Mitsnefes, Mark; Moxey-Mims, Marva; Dixon, John B.; Inge, Thomas H.
- Publisher
- Nature Publishing Group; Elsevier ; Elsevier Inc.; Elsevier BV; ScienceOpen (ISSN 0085-2538)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)