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Can I read Cerebral Oedema During Treatment of Diabetic Ketoacidosis: Are We Any Nearer Finding a Cause? on EtoBox?
Cerebral Oedema During Treatment of Diabetic Ketoacidosis: Are We Any Nearer Finding a Cause? by Julie A. Edge is a Medicine article available to read on EtoBox.
What is Cerebral Oedema During Treatment of Diabetic Ketoacidosis: Are We Any Nearer Finding a Cause? about?
Cerebral oedema remains the leading cause of death and morbidity in children with Type 1 diabetes mellitus. Around seven per thousand episodes of diabetic ketoacidosis (DKA) are complicated by cerebral oedema, and onequarter of those children will die from it. The cause or causes of cerebral oedema are still very poorly understood, but lawyers are already keen to implicate various aspects of the management of DKA. There have been many theories as to the pathophysiology of cerebral oedema, and possible contributing factors may be excessive rate of rehydration, falling plasma osmolality (particularly that due to a reduction in plasma sodium concentration), hypoxia and insulin dosage. There is some supportive evidence for all of these factors in some cases, but there have been no sizeable casecontrol studies, in part because of the rarity of the condition. Furthermore, cerebral oedema can still occur even when the management of DKA follows current `best practice' guidelines. As the mechanisms of cell volume regulation within the brain are increasingly understood, different questions may provide greater insights. For example, what is it about children that makes them so much more susce
Who reads Cerebral Oedema During Treatment of Diabetic Ketoacidosis: Are We Any Nearer Finding a Cause??
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Julie A. Edge
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1520-7552)
- Published
- 2000
- Language
- EN
- Field
- Medicine (Health Sciences)