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Essential Hypertension and Its Causes : Neural and Non-Neural Mechanisms by Paul I. Korner is a nonfiction available to read on EtoBox.

What is Essential Hypertension and Its Causes : Neural and Non-Neural Mechanisms about?

This new account of the pathogenesis of essential hypertension (EH) represents a detailed analysis of the main components of the circulatory control system. The latter's properties resemble those of man-made adaptive control systems in which regulatory parameters are altered when operating conditions exceed certain limits, often through neural mechanisms. Inheritance of EH depends on both genes and environment. The high blood pressure (BP) genes have not yet been definitively identified, whilst the main environmental causes are mental stress, high dietary salt intake and obesity. EH occurs as two major syndromes, each initiated by chronic stress: 1) Stress-and-salt related EH, and 2) Hypertensive obesity. Stress is perceived by the cortex, from which increased dopaminergic (DA) neuron activity stimulates the hypothalamic defense area, raising sympathetic neural activity (SNA) and BP. Normally these subside quickly when the stress is over, but in those susceptible to EH the DA synapses become sensitized so that the defense response is evoked by ever lower levels of stress. Sensitization is common in memory circuits, but not in autonomic neurons, so that this property in EH may be ge

Who reads Essential Hypertension and Its Causes : Neural and Non-Neural Mechanisms?

Author

Paul I. Korner

Publisher

Oxford University Press, USA

Published

2007

Language

EN

ISBN

9780190282547

Category

nonfiction

Subjects

Medical, Medicine