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A 65-year-old woman presents with confusion and lethargy. Lab tests show hyponatremia with a serum sodium of 108 mmol/L and normal kidney function. A CT scan shows no abnormalities. The most likely diagnosis is syndrome of inappropriate antidiuretic hormone secretion (SIADH). Treatment is fluid restriction and sodium supplementation to correct the hyponatremia while avoiding overly rapid correction. Complications of therapy include osmotic demyelination syndrome.
- Author
- Edwin Okon
- Language
- EN