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Humanized Mice Current Topics in Microbiology and Immmunology by Tatsuji Nomura; ‎Takeshi Watanabe; ‎Sonoko Habu is a nonfiction available to read on EtoBox.

What is Humanized Mice Current Topics in Microbiology and Immmunology about?

The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatment of human diseases in mice with good reproducibility. Thus, the hum- ized mouse can be used as a potent tool in both basic and clinical research in the future. The development of appropriate immunodeficient mice has been indispensable in the creation of the humanized mouse, which has been achieved through many years of efforts by several laboratories. The first stage on the road to the humanized mouse was the report on nude mice by Isaacson and Cattanach in 1962. Thereafter, nude mice were studied in detail by Falanagan and, in 1968, Pantelouris found that these mice have no thymus gland, which suggested that the mice lack transplan- tion immunity against xenografts such as human hematopoietic stem cells. At the Nude Mouse Workshops (organized by Regard, Povlsen, Nomura and co

Who reads Humanized Mice Current Topics in Microbiology and Immmunology?

Author

Tatsuji Nomura; ‎Takeshi Watanabe; ‎Sonoko Habu

Publisher

Springer Spektrum. in Springer-Verlag GmbH

Published

2008

Language

EN

ISBN

9783642420771

Category

nonfiction

Subjects

Medical, Science, Medicine