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What is A Predictive Mechanistic Model of Drug Release From Surface Eroding Polymeric Nanoparticles about?

This study presents a mechanistic model for drug release from surface eroding polymeric nanoparticles (NPs) made from polyanhydrides and acetalated dextran (Ace-DEX). The model, which incorporates drug diffusion and polymer degradation, was validated against various drug release profiles and demonstrated superior predictive accuracy compared to conventional models. The findings suggest that this predictive modeling approach can optimize drug release kinetics for enhanced therapeutic effects in future Ace-DE

Author

49vh53y26

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EN