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Three-dimensional Analysis of Regional Left Ventricular Endocardial Curvature from Cardiac Magnetic Resonance Images by Francesco Maffessanti; Roberto M. Lang; Johannes Niel; Regina Steringer-Mascherbauer; Enrico G. Caiani; Hans-Joachim Nesser; Victor Mor-Avi is a Medicine article available to read on EtoBox.

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## Purpose: Left ventricular (lv) remodeling is usually assessed using global changes in lv volume. we hypothesized that three-dimensional analysis of regional endocardial curvature from magnetic resonance images could provide clinically useful information on localized lv remodeling. we tested this approach by investigating regional differences in endocardial curvature in normal and hypokinetic ventricles. ## Materials and methods: Images were obtained in 44 patients with normal lv function (nl, n=14), dilated cardiomyopathy (dcm, n=15) or ischemic heart disease (ihd, n=15). local surface curvedness, normalized to take into account instantaneous lv size (c(n)), was calculated throughout the cardiac cycle and compared between segment groups: nl (n=401), ihd (n=92) and dcm (n=255). ## Results: In all normal segments, c(n) gradually increased during systole and then decreased during diastole. while both maximum and minimum values of c(n) were comparable in the basal and midventricular segments, they were significantly higher in the four apical segments and highest in the apical cap. in addition, percent change in c(n) was higher in mid and apical compared to basal segments (p<.05). at

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Author

Francesco Maffessanti; Roberto M. Lang; Johannes Niel; Regina Steringer-Mascherbauer; Enrico G. Caiani; Hans-Joachim Nesser; Victor Mor-Avi

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0730-725X)

Published

2011

Language

EN

Field

Medicine (Health Sciences)