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Myrochromanol analogues and trichothecene derivatives from the shellfish-derived fungus Albifimbria verrucaria by Sheng-Tao Fang; Yin-Ping Song; Feng-Ping Miao; Xiu-Li Yin; Nai-Yun Ji is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Myrochromanol analogues and trichothecene derivatives from the shellfish-derived fungus Albifimbria verrucaria about?
Eight myrochromanol analogues, including three pairs of epimers at C-2 with the myrochromanol scaffold and two examples of myrochromanol with sugar moiety linked at C-4, together with twelve trichothecene derivatives were isolated from the cultures of a shellfish-derived fungus Albifimbria verrucaria CD1-4. Among them, eight compounds named 2-epi-myrochromanol, ent-myrochromanol B, 4-epi-myrochromanol B, 2-epi-myrochromanol A, myrochromanosides A and B, 6′,7′-erythro-(2′E,4′Z)-trichoverrol B, 3R,8S-dihyroxyroridin H were previously undescribed fungal metabolites. Their planar structures and relative configurations were established by 1D and 2D NMR, and HR-MS data analysis, and their absolute configurations were determined using the modified Mosher's method and electronic circular dichrosim calculations. Almost all isolates were evaluated for growth rate inhibition of three marine harmful microalgae Chattonella marina, Heterosigma akashiwo, and Prorocentrum donghaiense, and lethal activity to one marine zooplankton, Artemia salina. Myrochromanosides A and B exhibited obvious inhibitory against three tested microalgae with IC50 values in the range of 9.2–108.9 μM. 8α-Hydroxyroridin H
Who reads Myrochromanol analogues and trichothecene derivatives from the shellfish-derived fungus Albifimbria verrucaria?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Sheng-Tao Fang; Yin-Ping Song; Feng-Ping Miao; Xiu-Li Yin; Nai-Yun Ji
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)