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Can I read The Longitudinal Relation Between Executive Functioning and Multilayer Network Topology in Glioma Patients on EtoBox?

The Longitudinal Relation Between Executive Functioning and Multilayer Network Topology in Glioma Patients by Marike R. van Lingen; Lucas C. Breedt; Jeroen J.G. Geurts; Arjan Hillebrand; Martin Klein; Mathilde C.M. Kouwenhoven; Shanna D. Kulik; Jaap C. Reijneveld; Cornelis J. Stam; Philip C. De Witt Hamer; Mona L.M. Zimmermann; Fernando A.N. Santos; Linda Douw is a Medicine article available to read on EtoBox.

What is The Longitudinal Relation Between Executive Functioning and Multilayer Network Topology in Glioma Patients about?

Many patients with glioma, primary brain tumors, suffer from poorly understood executive functioning deficits before and/or after tumor resection. We aimed to test whether frontoparietal network centrality of multilayer networks, allowing for integration across multiple frequencies, relates to and predicts executive functioning in glioma. Patients with glioma (n = 37) underwent resting-state magnetoencephalography and neuropsychological tests assessing word fluency, inhibition, and set shifting before (T1) and one year after tumor resection (T2). We constructed binary multilayer networks comprising six layers, with each layer representing frequency-specific functional connectivity between source-localized time series of 78 cortical regions. Average frontoparietal network multilayer eigenvector centrality, a measure for network integration, was calculated at both time points. Regression analyses were used to investigate associations with executive functioning. At T1, lower multilayer integration (__p =__ 0.017) and epilepsy (__p =__ 0.006) associated with poorer set shifting (adj. __R__^__2__^ = 0.269). Decreasing multilayer integration (__p =__ 0.022) and not undergoing chemotherap

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Author
Marike R. van Lingen; Lucas C. Breedt; Jeroen J.G. Geurts; Arjan Hillebrand; Martin Klein; Mathilde C.M. Kouwenhoven; Shanna D. Kulik; Jaap C. Reijneveld; Cornelis J. Stam; Philip C. De Witt Hamer; Mona L.M. Zimmermann; Fernando A.N. Santos; Linda Douw
Publisher
Springer Science and Business Media LLC
Published
2023
Language
EN
Field
Medicine (Health Sciences)

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