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Feasibility of Breast-conserving Therapy for Macroscopically Multiple Ipsilateral Breast Cancer by Setsuko Okumura; Michihide Mitsumori; Chikako Yamauchi; Sachiko Kawamura; Natsuo Oya; Yasushi Nagata; Masahiro Hiraoka; Masaki Kokubo; Keiichi Mise; Hiroshi Kodama is a Medicine article available to read on EtoBox.

What is Feasibility of Breast-conserving Therapy for Macroscopically Multiple Ipsilateral Breast Cancer about?

Purpose: Macroscopically multiple ipsilateral breast cancer (MMIBC) is generally considered a contraindication for breast-conserving therapy (BCT). The result of BCT for MMIBC is reported and the feasibility discussed. Methods and Materials: Between July 1993 and February 1999, 34 patients with MMIBC underwent BCT at our clinic. The local control, disease-free survival, and cosmetic results in these patients were compared with those of patients with single disease. Results: After wide excision, 21 (62%) of 34 patients with MMIBC had a close surgical margin and the rate was significantly greater than that of patients with a single lesion. However, the size of the boost irradiation field was not significantly increased. At a median follow-up of 98 months, no statistically significant difference was noted in local control, disease-free survival, or cosmetic result compared with patients with a single lesion. Conclusion: Although patients with MMIBC frequently had close surgical margins after BCT, it can be a treatment option for these patients as long as the close surgical margin is accurately detected and treated with an appropriate radiation technique.

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Author

Setsuko Okumura; Michihide Mitsumori; Chikako Yamauchi; Sachiko Kawamura; Natsuo Oya; Yasushi Nagata; Masahiro Hiraoka; Masaki Kokubo; Keiichi Mise; Hiroshi Kodama

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2004

Language

EN

Field

Medicine (Health Sciences)