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The study investigates genetic factors contributing to intracranial aneurysm (IA) susceptibility through a genome screen of multiplex families. Evidence of linkage was found on chromosomes 4, 7, 8, and 12, with potential gene-smoking interactions identified on chromosomes 4, 7, and 12. The research highlights the importance of both genetic and environmental factors, such as smoking and hypertension, in the risk of IA.

Author
Mateus Vinicius
Language
EN

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