Opening book details…
Can I read Orbital Plasmacytoma, An Uncommon Presentation of Advanced Multiple Myeloma on EtoBox?
Orbital Plasmacytoma, An Uncommon Presentation of Advanced Multiple Myeloma by Andreia Margarida de Matos; André Goulard; André Ribeiro; Ricardo Freitas; Catarina Monteiro; Paulo Martins is a Medicine article available to read on EtoBox.
What is Orbital Plasmacytoma, An Uncommon Presentation of Advanced Multiple Myeloma about?
## Introduction Extramedullary plasmacytomas are present in 13% of multiple myeloma (MM) patients. Less than 5% of MM cases are non-secretory. The orbital location is uncommon and a minority of orbital tumours are plasmacytomas. ## Description The patient was a 71-year-old man, with right proptosis, retro-ocular pain and epistaxis with visual acuity 2/10, limitation of upper eye movement and scattered ecchymosis. Blood tests revealed severe anaemia, coagulopathy, increased serum creatinine, LDH and C-RP without improvement after antimicrobial treatment. Peripheral immunophenotyping showed 9.4% of plasma cells with intracytoplasmic clonal κ chains. IgG and λ chains were decreased with normal plasma and urine immunofixation. Orbital CT: retro-orbital superomedial tumour with bone destruction. Histology of the tumour and bone biopsy was consistent with plasmacytoma. The patient was deceased in 2 weeks. ## Discussion MM accounts for 10% of haematopoietic tumours; 7% of cases present with plasmacytomas at diagnosis. Orbital locations are rarely reported (frequently in the temporal region). Proptosis, ptosis and reduced visual acuity are common symptoms. However, orbital pain is less fre
Who reads Orbital Plasmacytoma, An Uncommon Presentation of Advanced Multiple Myeloma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Andreia Margarida de Matos; André Goulard; André Ribeiro; Ricardo Freitas; Catarina Monteiro; Paulo Martins
- Publisher
- SMC Media
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)