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Can I read Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer on EtoBox?
Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer by Sung Jun Ma; Jasmin Gill; Olivia Waldman; Keerti Yendamuri; Cynthia Dunne-Jaffe; Udit Chatterjee; Fatemeh Fekrmandi; Rohil Shekher; Austin Iovoli; Song Yao; Oluwadamilola T. Oladeru; Anurag K. Singh is a Medicine article available to read on EtoBox.
What is Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer about?
Importance While low income has been associated with a higher incidence of triple-negative breast cancer, its association with 21-gene recurrence score (RS) among patients with estrogen receptor (ER)-positive breast cancer remains unclear. Objective To evaluate the association of household income with RS and overall survival (OS) among patients with ER-positive breast cancer. Design, Setting, and Participants This cohort study used data from the National Cancer Database. Eligible participants included women diagnosed between 2010 and 2018 with ER-positive, pT1-3N0-1aM0 breast cancer who received surgery followed by adjuvant endocrine therapy with or without chemotherapy. Data analysis was performed from July 2022 to September 2022. Exposures Low vs high neighborhood-level household income levels defined as below vs above the median household income of $50 353 based on each patient’s zip code. Main Outcomes and Measures RS (a score ranged from 0 to 100 based on gene expression signatures indicating the risk of distant metastasis, with RS of 25 or below indicating non–high risk and RS above 25 indicating high risk) and OS. Results Among 119 478 women (median [IQR] age, 60 [52-67] yea
Who reads Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sung Jun Ma; Jasmin Gill; Olivia Waldman; Keerti Yendamuri; Cynthia Dunne-Jaffe; Udit Chatterjee; Fatemeh Fekrmandi; Rohil Shekher; Austin Iovoli; Song Yao; Oluwadamilola T. Oladeru; Anurag K. Singh
- Publisher
- American Medical Association (AMA)
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)