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New computer-based approach for seeking a key step in the synthesis of complex structures. Application to Taxane and Crinipellin Diterpenoid Frameworks. by G. Mehta; R. Barone; P. Azario; F. Barberis; M. Arbelot; M. Chanon is a Chemistry article available to read on EtoBox.

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We describe a new approach to map the precursors of complex target structures, involving a key transform, employing a new version of our SOS program which works both backward andforward. In this approach target and reactions are coded on a skeleton model. Results obtainedfor two diterpenoidframavorks (taxane and crinipellin) of current interest are discussed.

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Author

G. Mehta; R. Barone; P. Azario; F. Barberis; M. Arbelot; M. Chanon

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)

Published

1992

Language

EN

Field

Chemistry (Physical Sciences)