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What is Population Stratification about?
This document discusses the impact of human population structure on genetic association studies, highlighting the risks of false positives and missed associations due to undetected population structure. It emphasizes the need for large sample sizes in studies and evaluates methods for correcting population structure, such as Genomic Control, while noting their limitations. The findings aim to guide the design of future large-scale association studies by quantifying population structure effects across differ
- Author
- Sarbajit Pathak
- Language
- EN