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Can I read β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action on EtoBox?
β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action by Jason Xiang; Manus Ipek; Vipin Suri; May Tam; Yuzhe Xing; Nelson Huang; Yanling Zhang; James Tobin; Tarek S. Mansour; John McKew is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action about?
The design, synthesis, and biological evaluation of b-keto sulfones as 11b-HSD1 inhibitors and the mechanism of inhibition are described here. This class of compounds is not active against 11b-HSD2 and therefore may have therapeutic potential for metabolic syndrome and type 2 diabetes.
Who reads β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Jason Xiang; Manus Ipek; Vipin Suri; May Tam; Yuzhe Xing; Nelson Huang; Yanling Zhang; James Tobin; Tarek S. Mansour; John McKew
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0968-0896)
- Published
- 2007
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)