Can I read TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer on EtoBox?

TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer by Dan Li, Bin Li and Hui Zhao is a book available to read on EtoBox.

What is TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer about?

The treatment and prognosis of advanced colorectal cancer (CRC) remain a challenging clinical research focus. TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer 1 Introduction 1 Results 3 TOX Is Downregulated in Human CRC Tissues From Patients With Poor Survival 3 Association Between TOX Expression and Clinicopathological Parameters for CRC 3 TOX Expression Is Higher in MSI CRC Than in MSS CRC, Positively Correlates With ImmuneScore and StromalScore, and Negatively Correlates With TumorPurity 4 TOX Expression Suppresses Cancer Cell Proliferation, Migration, Invasions, and Promotes Apoptosis in vitro 4 TOX Represses the Epithelial-Mesenchymal Transition 5 Rapamycin Partly Reverses the Aggressive Phenotype of TOX-Deficient Cells in vitro 7 TOX Acts as a Tumor Suppressor by Inhibiting Tumorigenesis and Metastasis in vivo 7 Rapamycin or PD1 Inhibition Suppresses Tumorigenesis 8 Materials and Methods 9 Patients 9 Immunohistochemical Assay (IHC) 9 Quantitative Real-Time Polymerase Chain Reaction 9 Western Blot 10 Bioinformatics Analysis 10 Cell Culture 10 Lentivirus Packaging 11 Cell Migration and Invasion Assays 11 Cell Proliferation Assay 11 Flow Cytometry

Author

Dan Li, Bin Li and Hui Zhao

Language

EN