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Rifampin has been utilized in combination therapy for orthopedic device-related infections (ODRI) for nearly three decades, demonstrating efficacy against staphylococcal biofilm infections in vitro and animal models. Its use is particularly indicated for patients with periprosthetic joint infections (PJI) who meet specific criteria, although careful consideration is necessary due to the risk of rapid resistance development. The review highlights the importance of rifampin in treating ODRIs, while also ackno

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laboratoriods.granadas

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EN