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Effects of Probiotics in the Treatment of Food Hypersensitivity in Children: a Systematic Review by Stephanie Campos dos Santos; Tulio Konstantyner; Renata Rodrigues Cocco is a Medicine article available to read on EtoBox.

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## Introduction: Food allergy is considered a public health problem for children. the modulation of the intestinal microbiota seems a promising strategy for the control of allergic reactions. ## Objective: To describe the effects of different forms of probiotics in pediatric food hypersensitivity treatment. ## Data source: We conducted a systematic review based on clinical trials published in the pubmed and web of science databases. the searches were carried out using the mesh terms "food hypersensitivity," "probiotics," "lactobacillus," and "bifidobacterium". ## Data synthesis: The final selection resulted in 18 clinical trials, which were predominantly samples of infants and pre-school children. the most-often used strain, either alone or in combination, was lactobacillus rhamnosus gg; a placebo was mainly used in the control group. as for the vehicle, the most common forms were capsules and infant formulas, and the period of intervention ranged from four weeks to 24 months, with weekly or monthly visits to measure the outcomes. in these 18 trials, 46 analyses were performed with 27 different types of outcomes to evaluate the effects of probiotics (12 laboratory and 15 clinical).

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Author

Stephanie Campos dos Santos; Tulio Konstantyner; Renata Rodrigues Cocco

Published

2019

Language

EN

Field

Medicine (Health Sciences)