Can I read Neurocognitive functioning in acute or early HIV infection on EtoBox?

Neurocognitive functioning in acute or early HIV infection by David J. Moore; for the CHARTER Group; Scott L. Letendre; Sheldon Morris; Anya Umlauf; Reena Deutsch; Davey M. Smith; Susan Little; Alexandra Rooney; Donald R. Franklin; Ben Gouaux; Shannon LeBlanc; Debra Rosario; Christine Fennema-Notestine; Robert K. Heaton; Ronald J. Ellis; J. Hampton Atkinson; Igor Grant is a scholarly article available to read on EtoBox.

What is Neurocognitive functioning in acute or early HIV infection about?

We examined neurocognitive functioning among persons with acute or early HIV infection (AEH) and hypothesized that the neurocognitive performance of AEH individuals would be intermediate between HIV seronegatives (HIV−) and those with chronic HIV infection. Comprehensive neurocognitive testing was accomplished with 39 AEH, 63 chronically HIV infected, and 38 HIV− participants. All AEH participants were HIV infected for less than 1 year. Average domain deficit scores were calculated in seven neurocognitive domains. HIV−, AEH, and chronically HIV infected groups were ranked from best (rank of 1) to worst (rank of 3) in each domain. All participants received detailed substance use, neuromedical, and psychiatric evaluations and HIV infected persons provided information on antiretroviral treatment and completed laboratory evaluations including plasma and CSF viral loads. A nonparametric test of ordered alternatives (Page test), and the appropriate nonparametric follow-up test, was used to evaluate level of neuropsychological (NP) functioning across and between groups. The median duration of infection for the AEH group was 16 weeks [interquartile range, IQR: 10.3–40.7] as compared to 4.9

Author

David J. Moore; for the CHARTER Group; Scott L. Letendre; Sheldon Morris; Anya Umlauf; Reena Deutsch; Davey M. Smith; Susan Little; Alexandra Rooney; Donald R. Franklin; Ben Gouaux; Shannon LeBlanc; Debra Rosario; Christine Fennema-Notestine; Robert K. Heaton; Ronald J. Ellis; J. Hampton Atkinson; Igor Grant

Publisher

Springer US; Springer-Verlag; Taylor and Francis Ltd; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1355-0284)

Published

2010

Language

EN