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Can I read Immunohistochemical Localization of Endothelin-like Immunoreactivity in Human Tooth Germ and Mature Dental Pulp on EtoBox?
Immunohistochemical Localization of Endothelin-like Immunoreactivity in Human Tooth Germ and Mature Dental Pulp by Andrea Casasco; Alberto Calligaro; Marco Casasco; David R. Springall; Patrizia Tenti; Carla Marchetti; Paola Poggi; Julia M. Polak is a Neuroscience article available to read on EtoBox.
What is Immunohistochemical Localization of Endothelin-like Immunoreactivity in Human Tooth Germ and Mature Dental Pulp about?
The distribution in oral tissues of endothelin, a multifunctional peptide originally identified within endothelial cells, and subsequently in some epithelial cells, neurons and neuroendocrine cells, has not been investigated yet. We have studied the localization of endothelin-like immunoreactivity in human tooth germ and mature dental pulp by immunohistochemical techniques. Such immunoreactivity was detected only within endothelial cells in both mature dental pulp and developing tooth. Arteries and veins of various sizes as well as small thin vessels displayed endothelin-like immunoreactivity. In the tooth germ, the cells of the enamel organ or the precursors of the odontoblasts were found unreactive. In the mature pulp, no cells of the stroma or nerves displayed endothelin-like immunoreactivity. These findings suggest that vascular endothelium may be the only source of endothelin in human dental tissues. It is tentatively proposed that endothelin released in mature tooth pulp may participate in the regulation of the pulpal blood flow. Although the possible role of endothelin in developing tissues is far from being clear, the mitogenic effects and the proto-oncogenes expression ind
Who reads Immunohistochemical Localization of Endothelin-like Immunoreactivity in Human Tooth Germ and Mature Dental Pulp?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Andrea Casasco; Alberto Calligaro; Marco Casasco; David R. Springall; Patrizia Tenti; Carla Marchetti; Paola Poggi; Julia M. Polak
- Publisher
- Springer; Springer-Verlag; Springer Verlag; J.F. Bergmann; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-2061)
- Published
- 1990
- Language
- EN
- Field
- Neuroscience (Life Sciences)