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Left ventricular‐only fusion pacing versus cardiac resynchronization therapy in heart failure patients: A randomized controlled trial by Yangang Su; Wei Hua; Farong Shen; Jiangang Zou; Baopeng Tang; Keping Chen; Yixiu Liang; Lang He; Xiaohong Zhou; Xue Zhang; Hongyang Lu; Shu Zhang is a Medicine article available to read on EtoBox.
What is Left ventricular‐only fusion pacing versus cardiac resynchronization therapy in heart failure patients: A randomized controlled trial about?
## Abstract ## Background It is unclear whether clinical benefits of cardiac resynchronization can be achieved by pacing only the left ventricle. ## Hypothesis We aimed to compare the effect of a novel adaptive left ventricular‐only fusion pacing (LVP) on ventricular function with conventional biventricular pacing (BVP) in cardiac resynchronization therapy (CRT) indicated patients. ## Methods This prospective, randomized, multicenter study enrolled CRT‐indicated patients with PR interval ≤ 200 ms who were randomized in the adaptive LVP group (using the AdaptivCRTTM algorithm with intentional non‐capture right ventricular pacing) or the echocardiography‐optimized BVP group. Cardiac function and echocardiography were evaluated at baseline and follow‐ups. CRT super response was defined as two‐fold or more increase of left ventricular ejection fraction (LVEF) or final LVEF >45%, and LV end‐systolic volume (LVESV) decrease >15%, and New York Heart Association (NYHA) class improved by at least one level. ## Results Sixty‐three patients were enrolled in the study (LVP = 34 vs. BVP = 29). At 6‐month follow‐up, significant improvements in LVEF, LVESV, and NYHA class were observed in both gr
Who reads Left ventricular‐only fusion pacing versus cardiac resynchronization therapy in heart failure patients: A randomized controlled trial?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Yangang Su; Wei Hua; Farong Shen; Jiangang Zou; Baopeng Tang; Keping Chen; Yixiu Liang; Lang He; Xiaohong Zhou; Xue Zhang; Hongyang Lu; Shu Zhang
- Publisher
- Wiley
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)