About this document
Kahan. 2014. Reducing Bias in Open-Label Trials Where Blinded Outcome Assessment Is Not Feasible by Eghar Everydayishell is a document available to read on EtoBox.
This document discusses strategies to reduce bias in open-label trials where blinded outcome assessment is not feasible, using two randomized trials as examples. The TRIGGER trial modified the definition of further bleeding to focus on objective measures, while the TAPPS trial adjusted the referral process for pleural drainage to involve both unblinded clinicians and a blinded assessor. The authors conclude that modifying outcome definitions or assessment methods can help mitigate bias when blinding is not
- Author
- Eghar Everydayishell
- Language
- EN