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The Healthy Volunteer in Clinical Pharmacology: Personality and Motivation by F. P. Meyer; F-W. Röhl; R. Haschke is a Medicine article available to read on EtoBox.

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The aim of the present study was to quantify the personality structure and motivation of medical students, who are often the most readily available source of healthy volunteers, since it has long been known that the pharmacodynamics and pharmacokinetics of drugs can be substantially modified by predominant personality traits (e.g. neuroticism, extraversion). Over the course of 4 years, a total of 337 subjects (165 males, 172 females) out of the 496 medical students asked, participated in the study after appropriate instruction. Students were tested using the Motivation Q-Sort method which, by means of questions ("questionnaire sort"), investigates whether a subject tends to react in a success-motivated (SM) or a failure-motivated (FM) mode. The variable measured is the so-called net hope (NH), where NH > 1.6 corresponds to SM and NH < -0.3 corresponds to FM. We also used the Freiburg Personality Inventory (FPI) as a suitable method of determining personality structure. The predominant traits of interest found were nervousness (FPI 1), extraversion (FPI E), and neuroticism (FPI N). In the first series of tests (primary selection), motivation only was determined in 337 volunteers. Th

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Author

F. P. Meyer; F-W. Röhl; R. Haschke

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0031-6970)

Published

1995

Language

EN

Field

Medicine (Health Sciences)