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Concordance of Quality of Life Assessments Following Pediatric Hematopoietic Stem Cell Transplantation by Rosemarie E. Feichtl; Barry Rosenfeld; Brad Tallamy; Mitchell S. Cairo; Stephen A. Sands is a Medicine article available to read on EtoBox.

What is Concordance of Quality of Life Assessments Following Pediatric Hematopoietic Stem Cell Transplantation about?

## Abstract __Purpose__: To examine the concordance between pediatric patient's self‐report and parent‐report regarding a patient's quality of life (QoL) prior to and following hematopoietic stem cell transplantation (HSCT) and to identify potential medical and demographic covariates of concordance. __Patients and Methods__: Utilizing the PedsQL 4.0, the longitudinal QoL data were obtained from 68 pediatric HSCT patient–parent dyads prior to and up to two years post‐transplantation. __Results__: Reliability based upon Intraclass Correlation Coefficients (ICC) indicates a parabolic pattern of concordance being significantly poorer in the acute phase of treatment 3 months post‐HSCT, followed by a return to pre‐transplant levels at subsequent assessments and a substantial rise at one‐ and two‐year follow‐up assessments (Baseline ICC = 0.42; 3 months = 0.11; 6 months = 0.54). Paired __t__‐tests further indicate that concordance was highest for observable domains of functioning (Physical and School) with greater inter‐rater discrepancies on the subjective domains (Emotional and Social) of QoL at baseline and 6 months post‐transplantation. __Conclusion__: Children typically rated their Q

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Author
Rosemarie E. Feichtl; Barry Rosenfeld; Brad Tallamy; Mitchell S. Cairo; Stephen A. Sands
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; FASEB (ISSN 1057-9249)
Published
2010
Language
EN
Field
Medicine (Health Sciences)

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