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Advanced Delivery and Therapeutic Applications of RNAi by Kun Cheng, Ram Mahato, Ram I. Mahato is a nonfiction available to read on EtoBox.

What is Advanced Delivery and Therapeutic Applications of RNAi about?

RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: * Mechanisms, Barriers, and Analysis of RNAi Delivery * Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective * Bioconjugation of siRNA for Site Specifi c Delivery * Nanoscale Delivery Systems for RNAi * Environmentally-Responsive Delivery Systems for RNAi * Light-sensitive RNAi * Viral-Mediated Delivery of shRNA and miRNA * RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease * miRNA as therapeutic agents and targets __Advanced Delivery and Therapeutic Applications of RNAi__ combin

Who reads Advanced Delivery and Therapeutic Applications of RNAi?

Author

Kun Cheng, Ram Mahato, Ram I. Mahato

Publisher

Wiley & Sons, Limited, John

Published

2013

Language

EN

ISBN

9781119976868

Category

nonfiction

Subjects

Science, Chemistry, Medical