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Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients by Chun-Jing Du; Jing-Yuan Liu; Hui Chen; Shuo Yan; Lin Pu; Hao-Feng Xiong; Pan Xiang; Chuan-Sheng Li; Ming Zhang; Ru-Ming Xie; Bu-Dong Chen; Ang Li is a Medicine article available to read on EtoBox.

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## Abstract ## Background Accurately differentiating pneumocystis from cytomegalovirus pneumonia is crucial for correct therapy selection in AIDS patients. Hence, the goal of this study was to compare the computerized tomography (CT) features of pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients and identify clinical hallmarks to accurately distinguish these two pathologies. ## Methods A total of 112 AIDS patients (78 with pneumocystis pneumonia and 34 cytomegalovirus pneumonia) at Beijing Ditan Hospital from January 2017 to May 2019 were included in this study. Two experienced chest radiologists retrospectively reviewed CT images for 17 features including ground-glass opacity, consolidation, nodules, and halo sign. Binary logistic regression analyses were conducted to identify the significant parameters that distinguished pneumocystis pneumonia from cytomegalovirus pneumonia. Correlations were analyzed by Pearson or Spearman correlation analyses. Result were considered significant if P < 0.05. ## Results The presence of consolidation, halo signs, and nodules (all P < 0.05) were significantly more frequent in patients with cytomegalovirus pneumonia than in those

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Author

Chun-Jing Du; Jing-Yuan Liu; Hui Chen; Shuo Yan; Lin Pu; Hao-Feng Xiong; Pan Xiang; Chuan-Sheng Li; Ming Zhang; Ru-Ming Xie; Bu-Dong Chen; Ang Li

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2012-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc.; Island Press (ISSN 2049-9957)

Published

2020

Language

EN

Field

Medicine (Health Sciences)