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Infergen: Engineered Interferon for Hepatitis C by VVB is a document available to read on EtoBox.
Interferons are a group of regulatory molecules called cytokines. Infergen is an engineered interferon that was approved for treating hepatitis C. It was designed based on the most common amino acid sequences found in natural interferons. A DNA sequence coding for Infergen was inserted into E. coli, which accumulated it as inclusion bodies. The inclusion bodies are harvested, solubilized, and the interferon is purified through chromatography. The final product is a 30mg/ml solution with a 24 month shelf lif
- Author
- VVB
- Language
- EN