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Positron emission tomography with F-18-fluorodeoxyglucose to evaluate the results of hepatic chemoembolization by João V. Vitola; Dominique Delbeke; Steven G. Meranze; Murray J. Mazer; C. Wright Pinson is a Medicine article available to read on EtoBox.

What is Positron emission tomography with F-18-fluorodeoxyglucose to evaluate the results of hepatic chemoembolization about?

## Background: Positron emission tomography (pet) using f-18-flurodeoxyglucose (18fdg) is an imaging modality allowing direct evaluation of cellular glucose metabolism. the purpose of this study was to examine the role of 18fdg-pet in monitoring chemoembolization therapy of patients with liver metastases from adenocarcinoma. ## Methods: Thirty-four hepatic lesions in 4 patients were evaluated with 18fdg-pet before and 2-3 months after interventional therapy. all patients underwent transcatheter arterial chemoembolization. a total of nine pet studies were performed. semiquantitative measurement of the metabolic activity of the lesions was performed using the standard uptake value (suv) of 18fdg. comparison was performed between sequential pet scans using student's t test for paired data analysis. the pet findings were also compared with tumor marker levels measured at the time of the pet scans. ## Results: Twenty-five of 34 lesions had decreased 18fdg uptake (suv = 8 +/- 2 vs. 3 +/- 1; p < 0.00001), as expected in successful tumor chemoembolization. these findings were associated with a significant decrease in serum tumor marker levels (86 +/- 4%; p < 0.05) after treatment. however,

Who reads Positron emission tomography with F-18-fluorodeoxyglucose to evaluate the results of hepatic chemoembolization?

Author

João V. Vitola; Dominique Delbeke; Steven G. Meranze; Murray J. Mazer; C. Wright Pinson

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1996

Language

EN

Field

Medicine (Health Sciences)