About this document
De Novo Purine Synthesis Overview by Paola is a document available to read on EtoBox.
1. Purines can be synthesized de novo from ribose-5-phosphate and other small molecules or salvaged from purine bases. 2. The de novo synthesis pathway involves 10 enzymatic steps that convert ribose-5-phosphate and glutamine to inosine monophosphate (IMP). 3. IMP can then be converted to adenosine monophosphate (AMP) or guanosine monophosphate (GMP) to form the purine nucleotides.
- Author
- Paola
- Language
- EN