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Depressive-, Cognitive- or Stroke-Related Risk Factors of Post-Stroke Depression: Which One Could Better Help Clinicians and Patients? by Rebecca Perrain; David Calvet; Vincent Guiraud; Lila Mekaoui; Jean-Louis Mas; Philip Gorwood is a Medicine article available to read on EtoBox.

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## Purpose Post-stroke depression (PSD) affects one third of stroke survivors, with multiple severe negative consequences. We aim to assess the weight of four different types of clinical risk factors for PSD. ## Patients and Methods We conducted a prospective cohort study in a stroke centre. After stroke, patients were assessed for cognitive performances, psychiatric standardized questionnaires and socio-demographic features. They were called three months after and assessed for major depressive episode using DSM criteria. ## Results PSD was diagnosed in 8 of the 59 (13.6%) patients enrolled in the study. After multivariate analysis, only “previous history of depressive episode” remained a significant predictive factor for PSD, the model explaining 19% of the total variance (OR=18.0; p=0.002). Patients with a previous history of depression had a 10-fold increased risk for PSD. ## Conclusion Previous history of depression is confirmed as a strong risk factor for PDS and allow the identification of an at-risk sub-group of patients.

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Author

Rebecca Perrain; David Calvet; Vincent Guiraud; Lila Mekaoui; Jean-Louis Mas; Philip Gorwood

Publisher

Dove

Published

2021

Language

EN

Field

Medicine (Health Sciences)